Clinical navigation is largely based on image data and we focus on fast image modalities allowing for feedback and control. Particularly, we study optical coherence tomography (OCT) for precise, high resolution image guidance, e.g., in soft tissue and cardiac interventions. In addition we are interested in ultrasound (US) as a complementary modality for soft tissue imaging. We study methods to estimate tissue properties from OCT and US, e.g., to obtain forces and elasticity, and we integrate image guidance with robotics, navigation and machine learning.
Selected publications
N. Gessert, S. Latus, Y. S. Abdelwahed, D. M. Leistner, M. Lutz, A. Schlaefer (2019). Bioresorbable Scaffold Visualization in IVOCT Images Using CNNs and Weakly Supervised Localization. SPIE Medical Imaging 2019: Image Processing. Accepted.
N. Gessert, J. Beringhoff, C. Otte, A. Schlaefer (2018). Force Estimation from OCT Volumes using 3D CNNs. Int J Comput Assist Radiol Surg. 13 (7), 1073–1082.
S. Latus, F. Griese, M. Gräser, M. Möddel, M. Schlüter, C. Otte, N. Gessert, T. Saathoff, T. Knopp, A. Schlaefer (2018). Towards bimodal intravascular OCT MPI volumetric imaging. Proceedings of SPIE Medical Imaging: Physics of Medical Imaging 10573E.
R. Berndt, R. Rusch, L. Hummitzsch, M. Lutz, K. Heß, K. Huenges, B. Panholzer, C. Otte, A. Haneya, G. Lutter, A. Schlaefer, J. Cremer, J. Groß (2017). Development of a new catheter prototype for laser thrombolysis under guidance of optical coherence tomography (OCT): validation of feasibility and efficacy in a preclinical model. Journal of Thrombosis and Thrombolysis. 43 (3), 352-360.
O. Shahin, A. Beširevic, M. Kleemann, A. Schlaefer (2014). Ultrasound-based tumor movement compensation during navigated laparoscopic liver interventions. Surg Endosc. 28 (5), 1734-1741.