Radiation therapy presents an effective and non-invasive option for cancer treatment. However, the use of ionizing radiation can also be harmful and the effects and side effects of irradiation need to be balanced. We develop algorithms and systems to identify the optimal trade-off among the various objectives, e.g., dose in the target, dose in critical structures, or treatment time.

3D Inverse Planning

Interactive Multi-Criteria Optimization

Planning for Motion Compensated Treatments


  • S. Gerlach, I. Kuhlemann, P. Jauer, R. Bruder, F. Ernst, C. Fürweger, A. Schlaefer (2016). Feasibility of robotic ultrasound guided SBRT of the prostate. CARS 2016 Proceedings, supplement of the International Journal of CARS accepted. [BibTex]

  • T. Viulet, O. Blanck, A. Schlaefer (2014). SU-E-T-258:Parallel Optimization of Beam Configurations for CyberKnife Treatments. Medical Physics. 41 (283), [doi] [BibTex]

  • T. Viulet, O. Blanck, A. Schlaefer (2014). SU-E-T-42:Analysis of Spatial Trade-Offs for a Spinal SRS Case. Medical Physics. 41 (231), [doi] [BibTex]

  • A. Schlaefer, T. Viulet, A. Muacevic, C. Fürweger (2013). Multicriteria optimization of the spatial dose distribution. Med Phys. 40 (12), 121720. [doi] [BibTex]

  • A. Schlaefer, S. Dieterich (2011). Feasibility of case-based beam generation for robotic radiosurgery. Artif Intell Med. 52 (2), 67-75. [doi] [BibTex]

  • T. Viulet, N. Rzezovski, A. Schlaefer (2011). Towards interactive planning for radiotherapy by three-dimensional iso-dose manipulation. [BibTex]

  • T. Viulet, N. Rzezovski, A. Schlaefer (2011). Three-Dimensional Isodose Surface Manipulation for Multi-Criteria Inverse Planning in Radiosurgery. [doi] [BibTex]

  • A. Schlaefer, T. Wolschon (2010). Optimizing the Trade-Off Between Number of Beam Starting Points and Plan Quality in Robotic Radiosurgery. [BibTex]